mesa.multiomics.multiomics_spatial.get_avg_expression_neighbors

mesa.multiomics.multiomics_spatial.get_avg_expression_neighbors(exp_df, spatial_knn_indices)

Calculate the average expression values over the neighbors of each data point.

Parameters:

• exp_df (pd.DataFrame) – The DataFrame to process. Each row represents a data point (e.g., a cell in single-cell data), and each column represents an attribute of the data points (e.g., gene expression values).

• spatial_knn_indices (np.ndarray) – The indices that represent the k-nearest neighbors for each data point in a spatial data structure.

Returns:

The resulting np.ndarray represents the average expression values over the neighbors of a data point.

Return type:

np.ndarray